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4In 2007, Barrangou et al. demonstrated for the first time the function of CRISPR/Cas9 as a defensive mechanism of bacteria against bacteriophage attacks by a technique called “plaquing” which builds upon the technique of “plating” bacteria on agar. Plaques of viruses on agar are areas without growth of bacteria due to viral attacks.

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There are an unsurprisingly large number of jokes about Heated Rivalry from Sherman, capped off by a bit in which the two pretend to make out with each other — and the entirety of Mumford & Sons get involved too.