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The next year, PacBio developed a new method to allow multiple sequencing passes on the same DNA molecule. Double stranded DNA templates were ligated to two single stranded adapters, creating what the company called a “SMRTbell template.” Sequencing began at a primer on one of the adaptors and could proceed multiple times per molecule due to circularization, in a process called rolling-circle amplification. This helped reduce PacBio’s error rates significantly.，更多细节参见雷电模拟器官方版本下载
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https://www.theinformation.com/briefings/openai-hires-meta-ai-researcher-previously-led-apples-models-team?rc=qmzset
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